I don't disagree with the dog bone idea, but once you begin to fiddle with customizing it a bit to get whatever else it is that you want for a design, you may find that it doesn't do it for you. One problem inherent with a dog bone is the two mains so close together between the knobs at either end. If it's just a means to a greater end, you'll be happy. If you don't like the back-and-forth, then it won't work for you.
In smaller spaces, I like the around-the-room shelf type. You can keep the aisles wide, you can even squeeze in an island mid-room that acts as both a turning wye and storage yard for assembled trains. But the key advantage is wider, or deeper, benchwork in the corners that allows more generous curves and placing industries there to keep the wall shelving shallow.
If you can't have such a layout due to having to store things in that room, build higher. Allow storage below the layout, and get the trains up where you'll appreciate the view more realistically...near chest or even throat level. It will be a bit more difficult to build, but that's a part of building anyway...overcoming challenges.
One detractor, though, is that around-the-walls means an access gate that must swing up, swing down, or swing wide.