Deere Lines, do you know what radius/diameter you are going to use for parallel tracks?
I ask because the tighter the radius/diameter, the more overhang you must anticipate when establishing center rail-to-center rail specs.
I recall Jim Barrett, on OGR, measured for the minimum c-to-c distance in an article with photographs and showed that 6.5" was needed when an 89' auto carrier encountered a Big Boy (or similarly large locomotive) on 072 curves. Now, if Jim had used 096 curved track, the minimum distance would have been less because the overhangs of the test car/loco would have been less. (I will check for the article to confirm the 6.5" figure.)
As others have said, study the NMRA standards and accept the fact with variances for: (1) track radii/diameters; and, (2) overhang based on the size of cars and locos there is no "rule of thumb."
Ok, well this is interesting. I would need to build a separate building or buy a larger home to accommodate 072, let alone 096 or larger track. Either that or throw out everything else including the furnace and oil tanks in the basement. Or only run 1 set of large engines/train cars at one time.

they better start making stuff weather proof for the big stuff.
I hope to use Gargraves track with Ross 054 turnouts and spacing of 5.5 or larger for curves in the layout as planned now in AnyRail. That will accommodate the largest I have currently, I believe, so I will just need to be cautious not to buy larger. That will make me stick to older stuff, but heck, I would rather that than the import stuff anyway. They are pretty and all, but Made in the USA is important to me. And they cost way to much for Chinese import stuff. If still Made in USA with steel on steel rather than rubber bands on steel, true to prototype, that would be different. Just my humble opinion.
Thanks for all the advice, it is appreciated.
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